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US vs UK trading



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This may sound like an odd question, but it is not immediately obvious to me. 
I am currently trading exclusively on the London Stock Exchange (using 
MetaStock v6.0). I cannot act upon all the signals that I explore--not enough 
funds to use all hits, not enough time to analyse them all, not enough profit 
if the criteria are too narrow. Therefore, I am currently only looking at a 
subset of 350-odd (so-called "biggest") stocks. They are very easily 
identified because there are two indices, the FTSE-100 and the FTSE-250, that 
make up these stocks.

I want to get more into US stocks now. Is there an equivalent way to create a 
similar group, without having to go through thousands of issues that I do not 
know? I am interested in the NYSE and/or AMEX and/or NASDAQ.

Other question: I do not want to use a UK based broker for US securities. 
Their commissions for US dealing are too high and often they will take orders 
only when the US markets are closed--very odd. 
Can anybody recommend a "good" execution-only broker who also deals with 
foreign clients? 
What level of commissions should I expect? 
Could I normally expect to be paid interest (at attractive rates) on cash 
balances in my account? 
Is nominee service such an issue in the US as it is over here?

Thanks for any advice you can give me

Wolf